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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621349
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kcnb2
Name: potassium voltage-gated channel subfamily B member 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcnb2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of KCNB2 mRNAPMID:25181051 PMID:30816183 PMID:32528016 PMID:34947998
Kcnb2increases methylationEXP 6480464CTDbisphenol A results in increased methylation of KCNB2 genePMID:28505145
Kcnb2decreases expressionISOKcnb2 (Mus musculus)6480464CTDbisphenol A results in decreased expression of KCNB2 mRNAPMID:31250031
Kcnb2decreases methylationISOKCNB2 (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of KCNB2 genePMID:31601247
Kcnb2multiple interactionsISOKcnb2 (Mus musculus)6480464CTDESR2 protein affects the reaction [bisphenol A results in decreased expression of KCNB2 mRNA]PMID:31250031
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