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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621242
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adamts4
Name: ADAM metallopeptidase with thrombospondin type 1 motif, 4
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adamts4decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of ADAMTS4 mRNAPMID:34947998
Adamts4increases expressionEXP 6480464CTDbisphenol A results in increased expression of ADAMTS4 mRNAPMID:25181051 PMID:30816183 PMID:32528016
Adamts4increases methylationEXP 6480464CTDbisphenol A results in increased methylation of ADAMTS4 genePMID:28505145
Adamts4increases expressionISOADAMTS4 (Homo sapiens)6480464CTDbisphenol A results in increased expression of ADAMTS4 mRNAPMID:27685785
Adamts4increases expressionISOAdamts4 (Mus musculus)6480464CTDbisphenol A results in increased expression of ADAMTS4 mRNAPMID:35598803
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