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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tgm2
Name: transglutaminase 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgm2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of TGM2 mRNA; bisphenol A results in decreased expression of TGM2 proteinPMID:22649256 PMID:30816183
Tgm2increases expressionEXP 6480464CTDbisphenol A results in increased expression of TGM2 mRNAPMID:25181051 PMID:32145629
Tgm2multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Estradiol] results in decreased expression of TGM2 mRNAPMID:26496021
Tgm2decreases expressionISOTGM2 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of TGM2 mRNAPMID:29275510
Tgm2decreases methylationISOTgm2 (Mus musculus)6480464CTDbisphenol A results in decreased methylation of TGM2 promoterPMID:27312807
Tgm2increases expressionISOTgm2 (Mus musculus)6480464CTDbisphenol A results in increased expression of TGM2 mRNAPMID:30951980 PMID:32156529 PMID:34585602
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