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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620103
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bad
Name: BCL2-associated agonist of cell death
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baddecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of BAD mRNAPMID:34947998
Badincreases expressionEXP 6480464CTDbisphenol A results in increased expression of BAD mRNAPMID:25181051 PMID:27296223 PMID:30816183 PMID:32528016
Badincreases phosphorylationEXP 6480464CTDbisphenol A results in increased phosphorylation of BAD proteinPMID:24884420
Baddecreases expressionISOBAD (Homo sapiens)6480464CTDbisphenol A results in decreased expression of BAD mRNA; bisphenol A results in decreased expression of BAD proteinPMID:21277958 PMID:26363213
Badincreases expressionISOBad (Mus musculus)6480464CTDbisphenol A results in increased expression of BAD mRNAPMID:26049153 PMID:32156529 PMID:33221593
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