GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Vegfa | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of VEGFA mRNA | PMID:19696011 PMID:30816183 PMID:35192832 | Vegfa | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of VEGFA mRNA; bisphenol A results in increased expression of VEGFA protein | PMID:11393178 PMID:21513798 PMID:25181051 PMID:30580332 PMID:31697385 | Vegfa | multiple interactions | EXP | | 6480464 | CTD | [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of VEGFA mRNA; [bisphenol A co-treated with Fructose] results in increased expression of VEGFA mRNA | PMID:25607892 PMID:27622962 | Vegfa | affects expression | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | bisphenol A affects the expression of VEGFA protein | PMID:24632125 | Vegfa | decreases expression | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | bisphenol A results in decreased expression of VEGFA mRNA; bisphenol A results in decreased expression of VEGFA protein | PMID:23672405 PMID:30352284 | Vegfa | decreases expression | ISO | Vegfa (Mus musculus) | 6480464 | CTD | bisphenol A analog results in decreased expression of VEGFA mRNA; bisphenol A results in decreased expression of VEGFA mRNA | PMID:20432243 PMID:26063408 | Vegfa | decreases secretion | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | bisphenol A results in decreased secretion of VEGFA protein | PMID:34174261 | Vegfa | increases expression | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | bisphenol A analog results in increased expression of VEGFA mRNA; bisphenol A results in increased expression of VEGFA mRNA; bisphenol A results in increased expression of VEGFA protein | PMID:22045264 PMID:24793927 PMID:25333893 PMID:25982407 PMID:28964603 PMID:32387340 PMID:33670352 | Vegfa | increases secretion | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | bisphenol A results in increased secretion of VEGFA protein | PMID:18252963 | Vegfa | increases secretion | ISO | Vegfa (Mus musculus) | 6480464 | CTD | bisphenol A results in increased secretion of VEGFA protein | PMID:35051763 | Vegfa | multiple interactions | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [bisphenol A results in increased expression of VEGFA protein]; [bisphenol A co-treated with Fulvestrant] results in increased methylation of VEGFA gene; bisphenol A promotes the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; bisphenol A results in increased expression of and results in increased secretion of VEGFA protein; Fulvestrant inhibits the reaction [bisphenol A results in increased secretion of VEGFA protein] | PMID:18252963 PMID:25982407 PMID:28964603 PMID:30851587 PMID:31601247 | Vegfa | multiple interactions | ISO | Vegfa (Mus musculus) | 6480464 | CTD | 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [bisphenol A results in increased secretion of VEGFA protein]; [Caffeine co-treated with bisphenol A] results in decreased expression of VEGFA mRNA; [Caffeine co-treated with bisphenol A] results in decreased expression of VEGFA protein; bisphenol A inhibits the reaction [Streptozocin results in decreased secretion of VEGFA protein]; ESR2 protein affects the reaction [bisphenol A results in increased secretion of VEGFA protein] | PMID:31756439 PMID:35051763 | | ||||||||||||||||||||||
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