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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619716
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sv2b
Name: synaptic vesicle glycoprotein 2b
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sv2bdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of SV2B mRNAPMID:25181051
Sv2bincreases methylationEXP 6480464CTDbisphenol A results in increased methylation of SV2B genePMID:28505145
Sv2bmultiple interactionsEXP 6480464CTD[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of SV2B promoterPMID:23359474
Sv2bdecreases expressionISOSv2b (Mus musculus)6480464CTDbisphenol A results in decreased expression of SV2B mRNAPMID:30951980
Sv2bincreases expressionISOSv2b (Mus musculus)6480464CTDbisphenol A results in increased expression of SV2B mRNAPMID:32365465
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