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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61882
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr4a3
Name: nuclear receptor subfamily 4, group A, member 3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr4a3decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of NR4A3 mRNAPMID:25181051
Nr4a3increases expressionEXP 6480464CTDbisphenol A results in increased expression of NR4A3 mRNAPMID:26141625
Nr4a3multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of NR4A3 promoterPMID:23359474
Nr4a3affects methylationISONr4a3 (Mus musculus)6480464CTDbisphenol A affects the methylation of NR4A3 promoterPMID:27334623
Nr4a3decreases expressionISONR4A3 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of NR4A3 mRNAPMID:27685785
Nr4a3decreases expressionISONr4a3 (Mus musculus)6480464CTDbisphenol A results in decreased expression of NR4A3 mRNAPMID:25594700 PMID:37611474
Nr4a3increases expressionISONr4a3 (Mus musculus)6480464CTDbisphenol A results in increased expression of NR4A3 mRNAPMID:14967926 PMID:32156529
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