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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3798
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Syn2
Name: synapsin II
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Syn2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of SYN2 mRNAPMID:25181051 PMID:26186136
Syn2increases methylationEXP 6480464CTDbisphenol A results in increased methylation of SYN2 genePMID:28505145
Syn2multiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SYN2 mRNAPMID:36041667
Syn2decreases methylationISOSYN2 (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of SYN2 genePMID:31601247
Syn2increases expressionISOSyn2 (Mus musculus)6480464CTDbisphenol A results in increased expression of SYN2 mRNAPMID:20739668
Syn2increases methylationISOSyn2 (Mus musculus)6480464CTDbisphenol A results in increased methylation of SYN2 promoterPMID:27312807
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