GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fos | affects expression | EXP | | 6480464 | CTD | bisphenol A metabolite affects the expression of FOS mRNA | PMID:20435109 | Fos | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of FOS mRNA | PMID:29552716 PMID:34947998 | Fos | increases activity | EXP | | 6480464 | CTD | bisphenol A results in increased activity of FOS protein | PMID:22446810 | Fos | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of FOS mRNA; bisphenol A results in increased expression of FOS protein | PMID:10706531 PMID:25181051 PMID:27743673 PMID:9607780 | Fos | multiple interactions | EXP | | 6480464 | CTD | Phytochemicals inhibits the reaction [bisphenol A results in increased activity of FOS protein] | PMID:22446810 | Fos | affects expression | ISO | FOS (Homo sapiens) | 6480464 | CTD | bisphenol A affects the expression of FOS mRNA | PMID:20170705 | Fos | affects methylation | ISO | Fos (Mus musculus) | 6480464 | CTD | bisphenol A affects the methylation of FOS promoter | PMID:27334623 | Fos | decreases expression | ISO | FOS (Homo sapiens) | 6480464 | CTD | bisphenol A results in decreased expression of FOS mRNA | PMID:36232920 | Fos | increases expression | ISO | Fos (Mus musculus) | 6480464 | CTD | bisphenol A results in increased expression of FOS; bisphenol A results in increased expression of FOS mRNA | PMID:12021184 PMID:20826375 PMID:21813366 PMID:23274518 | Fos | increases expression | ISO | FOS (Homo sapiens) | 6480464 | CTD | bisphenol A results in increased expression of FOS mRNA; bisphenol A results in increased expression of FOS protein | PMID:20875696 PMID:22552965 PMID:24308608 PMID:26224478 PMID:31016847 | Fos | multiple interactions | ISO | Fos (Mus musculus) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Fulvestrant co-treated with bisphenol A] results in increased expression of FOS mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A promotes the reaction [FOS protein binds to GPER1 promoter]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of FOS mRNA]; [Fulvestrant co-treated with bisphenol A] results in increased expression of FOS mRNA; AG 1879 inhibits the reaction [bisphenol A promotes the reaction [FOS protein binds to GPER1 promoter]]; bisphenol A inhibits the reaction [Potassium results in increased expression of FOS mRNA]; bisphenol A promotes the reaction [FOS protein binds to GPER1 promoter]; ESR1 affects the reaction [bisphenol A results in increased expression of FOS mRNA]; FOS protein affects the reaction [bisphenol A results in increased expression of GPER1 mRNA]; FOS protein affects the reaction [bisphenol A results in increased expression of GPER1 protein]; FOS protein affects the reaction [bisphenol A results in increased phosphorylation of ESR1 protein]; FOS protein affects the reaction [bisphenol A results in increased phosphorylation of MAPK1 protein]; FOS protein affects the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of FOS mRNA]; GPER1 affects the reaction [bisphenol A results in increased expression of FOS mRNA]; GPER1 protein affects the reaction [[Fulvestrant co-treated with bisphenol A] results in increased expression of FOS mRNA]; KT 5823 inhibits the reaction [bisphenol A promotes the reaction [FOS protein binds to GPER1 promoter]]; Pertussis Toxin inhibits the reaction [bisphenol A promotes the reaction [FOS protein binds to GPER1 promoter]]; RTKI cpd inhibits the reaction [[Fulvestrant co-treated with bisphenol A] results in increased expression of FOS mRNA]; RTKI cpd inhibits the reaction [bisphenol A promotes the reaction [FOS protein binds to GPER1 promoter]]; RTKI cpd inhibits the reaction [bisphenol A results in increased expression of FOS mRNA] | PMID:15527870 PMID:21813366 PMID:23274518 PMID:28446726 | Fos | multiple interactions | ISO | FOS (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of FOS mRNA]; bisphenol A affects the reaction [Doxorubicin affects the expression of FOS mRNA]; bisphenol A inhibits the reaction [Doxorubicin results in decreased expression of FOS mRNA]; GPER1 mRNA affects the reaction [bisphenol A results in increased expression of FOS protein]; GPER1 protein promotes the reaction [bisphenol A results in increased expression of FOS mRNA]; TGFB3 protein inhibits the reaction [bisphenol A results in increased expression of FOS mRNA] | PMID:20875696 PMID:22552965 PMID:26224478 PMID:26320837 PMID:31470548 | | ||||||||||||||||||||||
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