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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2307
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cd44
Name: CD44 molecule
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cd44affects expressionEXP 6480464CTDbisphenol A affects the expression of CD44 mRNAPMID:25181051
Cd44decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of CD44 mRNAPMID:34947998
Cd44increases expressionEXP 6480464CTDbisphenol A results in increased expression of CD44 mRNAPMID:33296240
Cd44increases methylationEXP 6480464CTDbisphenol A results in increased methylation of CD44 genePMID:28505145
Cd44multiple interactionsEXP 6480464CTD[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CD44 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CD44 mRNAPMID:25607892
Cd44decreases expressionISOCd44 (Mus musculus)6480464CTDbisphenol A results in decreased expression of CD44 mRNA; bisphenol A results in decreased expression of CD44 proteinPMID:35999755 PMID:37105096
Cd44decreases expressionISOCD44 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of CD44 mRNA; bisphenol A results in decreased expression of CD44 proteinPMID:20678512 PMID:22576693 PMID:34186270
Cd44increases expressionISOCD44 (Homo sapiens)6480464CTDbisphenol A results in increased expression of CD44 mRNAPMID:18007998 PMID:26546977 PMID:28711546
Cd44multiple interactionsISOCd44 (Mus musculus)6480464CTD[bisphenol A co-treated with Tretinoin] results in decreased expression of CD44 mRNAPMID:30951980
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