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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1616662
Species: Mus musculus
RGD Object: Gene
Symbol: Kcnc4
Name: potassium voltage gated channel, Shaw-related subfamily, member 4
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcnc4increases expressionEXP 6480464CTDbisphenol A results in increased expression of KCNC4 mRNAPMID:31250031
Kcnc4increases methylationEXP 6480464CTDbisphenol A results in increased methylation of KCNC4 promoterPMID:27312807
Kcnc4decreases expressionISOKcnc4 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of KCNC4 mRNAPMID:25181051
Kcnc4increases methylationISOKcnc4 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of KCNC4 genePMID:28505145
Kcnc4multiple interactionsISOKCNC4 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in decreased methylation of KCNC4 genePMID:31601247
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