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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1566332
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pdhx
Name: pyruvate dehydrogenase complex, component X
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdhxaffects expressionEXP 6480464CTDbisphenol A affects the expression of PDHX mRNAPMID:25181051
Pdhxdecreases expressionISOPDHX (Homo sapiens)6480464CTDbisphenol A results in decreased expression of PDHX proteinPMID:34186270
Pdhxdecreases expressionISOPdhx (Mus musculus)6480464CTDbisphenol A results in decreased expression of PDHX mRNAPMID:33221593
Pdhxincreases expressionISOPDHX (Homo sapiens)6480464CTDbisphenol A results in increased expression of PDHX proteinPMID:37567409
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