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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306422
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cct7
Name: chaperonin containing TCP1 subunit 7
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cct7increases expressionEXP 6480464CTDbisphenol A results in increased expression of CCT7 mRNAPMID:25181051
Cct7multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Testosterone] results in increased expression of CCT7 mRNA; [bisphenol A co-treated with tributyltin] results in increased expression of CCT7 mRNAPMID:26496021 PMID:31129395
Cct7decreases expressionISOCCT7 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of CCT7 proteinPMID:34186270
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