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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304832
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aars1
Name: alanyl-tRNA synthetase 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aars1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of AARS1 mRNAPMID:33296240 PMID:34947998
Aars1increases expressionEXP 6480464CTDbisphenol A results in increased expression of AARS1 mRNAPMID:25181051 PMID:32145629
Aars1affects expressionISOAARS1 (Homo sapiens)6480464CTDbisphenol A affects the expression of AARS1 mRNAPMID:30903817
Aars1decreases expressionISOAARS1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of AARS1 proteinPMID:31675489 PMID:37567409
Aars1decreases expressionISOAars1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of AARS1 mRNAPMID:33221593
Aars1decreases methylationISOAars1 (Mus musculus)6480464CTDbisphenol A results in decreased methylation of AARS1 promoterPMID:27312807
Aars1increases expressionISOAARS1 (Homo sapiens)6480464CTDbisphenol A results in increased expression of AARS1 mRNA; bisphenol A results in increased expression of AARS1 proteinPMID:29275510 PMID:33670352 PMID:34186270
Aars1increases expressionISOAars1 (Mus musculus)6480464CTDbisphenol A results in increased expression of AARS1 mRNAPMID:38074096
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