Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303178
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nanog
Name: Nanog homeobox
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nanogdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of NANOG mRNA; bisphenol A results in decreased expression of NANOG proteinPMID:24134786 PMID:25181051
Nanogincreases expressionISONANOG (Homo sapiens)6480464CTDbisphenol A results in increased expression of NANOG mRNA; bisphenol A results in increased expression of NANOG proteinPMID:23391485 PMID:24424067 PMID:37610061 PMID:37834465
Nanogincreases expressionISONanog (Mus musculus)6480464CTDbisphenol A results in increased expression of NANOG mRNA; bisphenol A results in increased expression of NANOG proteinPMID:24090592 PMID:31288075
Nanogmultiple interactionsISONANOG (Homo sapiens)6480464CTD[bisphenol A co-treated with perfluorooctane sulfonic acid] results in decreased expression of NANOG mRNA; [bisphenol A co-treated with perfluorooctanoic acid co-treated with bisphenol S co-treated with perfluorooctane sulfonic acid] results in decreased expression of NANOG mRNAPMID:37834465
Nanogmultiple interactionsISONanog (Mus musculus)6480464CTD[bisphenol A co-treated with Stigmasterol] results in decreased expression of NANOG mRNA; bisphenol A inhibits the reaction [GW 4064 results in decreased expression of NANOG mRNA]PMID:30245210
Go Back to source page   Continue to Ontology report