GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ptgs2 | increases expression | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | Calcimycin results in increased expression of PTGS2 mRNA; Calcimycin results in increased expression of PTGS2 protein | PMID:19782052 PMID:25451590 PMID:9013627 | Ptgs2 | multiple interactions | ISO | PTGS2 (Homo sapiens) | 6480464 | CTD | [IL1B protein co-treated with Calcimycin] results in increased activity of PTGS2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of PTGS2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of PTGS2 protein; Calcimycin promotes the reaction [[Hydrogen Peroxide co-treated with Vanadates] results in increased expression of PTGS2 mRNA alternative form]; resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of PTGS2 mRNA]; resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of PTGS2 protein]; tert-Butylhydroperoxide inhibits the reaction [Acetaminophen inhibits the reaction [Calcimycin promotes the reaction [IL1B protein results in increased activity of PTGS2 protein]]] | PMID:10837497 PMID:15705740 PMID:19416633 | Ptgs2 | multiple interactions | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | shikonin inhibits the reaction [Calcimycin results in increased expression of PTGS2 mRNA] | PMID:25451590 | | ||||||||||||||||||||||
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