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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68384
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccnd1
Name: cyclin D1
Acc ID: CHEBI:33007
Term: chromium(6+)
Definition: A monoatomic hexacation that has formula Cr.
Chemical ID: MESH:C074702
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccnd1decreases expressionEXP 6480464CTDchromium hexavalent ion results in decreased expression of CCND1 proteinPMID:21621607 PMID:28077780
Ccnd1increases expressionEXP 6480464CTDchromium hexavalent ion results in increased expression of CCND1 mRNA; chromium hexavalent ion results in increased expression of CCND1 proteinPMID:30690063 PMID:32679048
Ccnd1multiple interactionsEXP 6480464CTDAscorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCND1 protein]PMID:21621607
Ccnd1increases expressionISOCCND1 (Homo sapiens)6480464CTDchromium hexavalent ion results in increased expression of CCND1 mRNAPMID:30690063
Ccnd1multiple interactionsISOCcnd1 (Mus musculus)6480464CTD[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of CCND1 mRNA; SHH protein affects the reaction [[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of CCND1 mRNA]PMID:31756458
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