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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:33007
Term: chromium(6+)
Definition: A monoatomic hexacation that has formula Cr.
Chemical ID: MESH:C074702
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bincreases expressionEXP 6480464CTDchromium hexavalent ion results in increased expression of IL1B proteinPMID:35024197
Il1bmultiple interactionsEXP 6480464CTDResveratrol inhibits the reaction [chromium hexavalent ion results in increased expression of IL1B protein]PMID:35024197
Il1bincreases secretionISOIL1B (Homo sapiens)6480464CTDchromium hexavalent ion results in increased secretion of IL1B proteinPMID:25448439
Il1bmultiple interactionsISOIl1b (Mus musculus)6480464CTD[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of IL1B mRNA; Acetylcysteine inhibits the reaction [[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of IL1B protein]PMID:36880428
Il1bmultiple interactionsISOIL1B (Homo sapiens)6480464CTDLuteolin inhibits the reaction [chromium hexavalent ion results in increased secretion of IL1B protein]PMID:25448439
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