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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731942
Species: Homo sapiens
RGD Object: Gene
Symbol: CACNA2D1
Name: calcium voltage-gated channel auxiliary subunit alpha2delta 1
Acc ID: CHEBI:32588
Term: potassium chloride
Definition: A metal chloride salt with a K(+) counterion.
Chemical ID: MESH:D011189
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CACNA2D1multiple interactionsISOCacna2d1 (Mus musculus)6480464CTD[gabapentin binds to and results in decreased activity of CACNA2D1 protein] which results in decreased susceptibility to Potassium Chloride; [gabapentin results in decreased activity of CACNA2D1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]; CACNA2D1 protein affects the reaction [Potassium Chloride results in increased transport of Calcium]PMID:17442347 PMID:17881535
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