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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70884 Species: Rattus norvegicus RGD Object: Gene Symbol: Eif2ak3 Name: eukaryotic translation initiation factor 2 alpha kinase 3

Acc ID: CHEBI:32585 Term: 4-hydroxynon-2-enal Definition: A hydroxyaldehyde that has formula C9H16O2. CasRN: 29343-52-0 Chemical ID: MESH:C027576

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases phosphorylation	ISO	RGD:736260	6480464	CTD	4-hydroxy-2-nonenal results in increased phosphorylation of EIF2AK3 protein	PMID:19041636