GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tlr4 | decreases activity | ISO | TLR4 (Homo sapiens) | 6480464 | CTD | 4-hydroxy-2-nonenal results in decreased activity of TLR4 protein | PMID:19627980 | Tlr4 | multiple interactions | ISO | TLR4 (Homo sapiens) | 6480464 | CTD | 4-hydroxy-2-nonenal inhibits the reaction [TLR4 protein binds to TLR4 protein] | PMID:19627980 | Tlr4 | multiple interactions | ISO | Tlr4 (Mus musculus) | 6480464 | CTD | 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]; 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]]; Dithiothreitol inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]]; Dithiothreitol inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]] | PMID:19627980 | | ||||||||||||||||||||||
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