• View As List
• View As Table

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734356 Species: Homo sapiens RGD Object: Gene Symbol: JUN Name: jun proto-oncogene

Acc ID: CHEBI:32509 Term: pirinixic acid Definition: An aryl sulfide that has formula C14H14ClN3O2S. CasRN: 50892-23-4 Chemical ID: MESH:C006253

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	[FOS protein co-treated with JUN protein] inhibits the reaction [pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]] pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]] pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA] pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]	PMID:17360982
multiple interactions	ISO	RGD:10828	6480464	CTD	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of JUN mRNA	PMID:19710929
multiple interactions	ISO	RGD:10828	6480464	CTD	PPARA protein promotes the reaction [pirinixic acid results in increased expression of JUN mRNA]	PMID:18467677
increases expression	ISO	RGD:10828	6480464	CTD	pirinixic acid results in increased expression of JUN mRNA	PMID:18467677 PMID:9013627 PMID:18445702
increases expression	ISO	RGD:10828	6480464	CTD	pirinixic acid results in increased expression of JUN mRNA	PMID:18445702 PMID:9013627 PMID:18467677
increases expression	ISO	RGD:10828	6480464	CTD	pirinixic acid results in increased expression of JUN mRNA	PMID:9013627 PMID:18445702 PMID:18467677
increases expression	ISO	RGD:10828	6480464	CTD	pirinixic acid results in increased expression of JUN mRNA	PMID:18445702 PMID:9013627 PMID:18467677 PMID:8764118
increases expression	ISO	RGD:10828	6480464	CTD	pirinixic acid results in increased expression of JUN mRNA	PMID:9013627 PMID:18467677 PMID:8764118 PMID:18445702
increases expression	ISO	RGD:10828	6480464	CTD	pirinixic acid results in increased expression of JUN mRNA	PMID:9013627 PMID:18467677 PMID:18445702 PMID:8764118
increases expression	ISO	RGD:10828	6480464	CTD	pirinixic acid results in increased expression of JUN protein	PMID:20025956
increases expression	ISO	RGD:10828	6480464	CTD	pirinixic acid results in increased expression of JUN mRNA	PMID:18445702 PMID:18467677 PMID:8764118 PMID:9013627