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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733729 Species: Homo sapiens RGD Object: Gene Symbol: MLH1 Name: mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)

Acc ID: CHEBI:32509 Term: pirinixic acid Definition: An aryl sulfide that has formula C14H14ClN3O2S. CasRN: 50892-23-4 Chemical ID: MESH:C006253

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:620937	6480464	CTD	pirinixic acid results in increased expression of MLH1 mRNA	PMID:20127075 PMID:19162173
increases expression	ISO	RGD:620937	6480464	CTD	pirinixic acid results in increased expression of MLH1 mRNA	PMID:19162173 PMID:20127075