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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731324 Species: Homo sapiens RGD Object: Gene Symbol: ODC1 Name: ornithine decarboxylase 1

Acc ID: CHEBI:32509 Term: pirinixic acid Definition: An aryl sulfide that has formula C14H14ClN3O2S. CasRN: 50892-23-4 Chemical ID: MESH:C006253

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:3227	6480464	CTD	pirinixic acid results in increased expression of ODC1 mRNA	PMID:15890375 PMID:19162173 PMID:17164430
multiple interactions	EXP		6480464	CTD	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ODC1 mRNA	PMID:19710929
increases expression	ISO	RGD:1551973	6480464	CTD	pirinixic acid results in increased expression of ODC1 mRNA	PMID:18445702 PMID:18301758
increases expression	ISO	RGD:1551973	6480464	CTD	pirinixic acid results in increased expression of ODC1 mRNA	PMID:18301758 PMID:18445702
increases expression	ISO	RGD:3227	6480464	CTD	pirinixic acid results in increased expression of ODC1 mRNA	PMID:17164430 PMID:15890375 PMID:19162173
increases expression	ISO	RGD:3227	6480464	CTD	pirinixic acid results in increased expression of ODC1 mRNA	PMID:19162173 PMID:15890375 PMID:17164430
increases expression	ISO	RGD:3227	6480464	CTD	pirinixic acid results in increased expression of ODC1 mRNA	PMID:15890375 PMID:17164430 PMID:19162173