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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfe2l2
Name: NFE2 like bZIP transcription factor 2
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l2decreases expressionISONfe2l2 (Mus musculus)6480464CTDpirinixic acid results in decreased expression of NFE2L2 mRNAPMID:18445702 PMID:20936131
Nfe2l2increases activityISONfe2l2 (Mus musculus)6480464CTDpirinixic acid results in increased activity of NFE2L2 proteinPMID:30114225 PMID:30203046
Nfe2l2increases expressionISONfe2l2 (Mus musculus)6480464CTDpirinixic acid results in increased expression of NFE2L2 mRNAPMID:16985257
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