GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Stat3 | decreases expression | ISO | Stat3 (Mus musculus) | 6480464 | CTD | pirinixic acid results in decreased expression of STAT3 mRNA | PMID:17321000 | Stat3 | increases expression | ISO | Stat3 (Mus musculus) | 6480464 | CTD | pirinixic acid results in increased expression of STAT3 mRNA | PMID:18445702 | Stat3 | multiple interactions | ISO | Stat3 (Mus musculus) | 6480464 | CTD | pirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased phosphorylation of STAT3 protein]; PPARA protein affects the reaction [pirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased phosphorylation of STAT3 protein]]; PPARA protein affects the reaction [pirinixic acid results in decreased expression of STAT3 mRNA] | PMID:17321000 PMID:27853831 | |
Go Back to source page | Continue to Ontology report |