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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2070
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Agtr1a
Name: angiotensin II receptor, type 1a
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agtr1aaffects expressionEXP 6480464CTDpirinixic acid affects the expression of AGTR1A mRNAPMID:19483382
Agtr1adecreases expressionEXP 6480464CTDpirinixic acid results in decreased expression of AGTR1A mRNA; pirinixic acid results in decreased expression of AGTR1A proteinPMID:18300857 PMID:19162173
Agtr1adecreases expressionISOAgtr1a (Mus musculus)6480464CTDpirinixic acid results in decreased expression of AGTR1A mRNAPMID:25270620
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