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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1313526 Species: Mus musculus RGD Object: Gene Symbol: Mki67 Name: antigen identified by monoclonal antibody Ki 67

Acc ID: CHEBI:32509 Term: pirinixic acid Definition: An aryl sulfide that has formula C14H14ClN3O2S. CasRN: 50892-23-4 Chemical ID: MESH:C006253

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	EXP		6480464	CTD	pirinixic acid results in increased expression of MKI67 mRNA	PMID:17950772
multiple interactions	EXP		6480464	CTD	PPARA protein promotes the reaction [pirinixic acid results in increased expression of MKI67 mRNA]	PMID:17950772
increases expression	ISO	RGD:1305476	6480464	CTD	pirinixic acid results in increased expression of MKI67 mRNA	PMID:22484513