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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3336
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pklr
Name: pyruvate kinase L/R
Acc ID: CHEBI:32497
Term: thioacetamide
Definition: A thiocarboxamide consiting of acetamide having the oxygen replaced by sulfur.
Chemical ID: MESH:D013853
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pklraffects expressionEXP 6480464CTDThioacetamide affects the expression of PKLR mRNAPMID:19483382
Pklrdecreases expressionEXP 6480464CTDThioacetamide results in decreased expression of PKLR mRNAPMID:23411599 PMID:28903497 PMID:34492290
Pklrmultiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of PKLR mRNAPMID:28943392
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