GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccl2 | affects expression | EXP | | 6480464 | CTD | titanium dioxide affects the expression of CCL2 mRNA | PMID:30012374 | Ccl2 | increases expression | EXP | | 6480464 | CTD | titanium dioxide results in increased expression of CCL2 | PMID:22939914 | Ccl2 | increases expression | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | titanium dioxide results in increased expression of CCL2 mRNA; titanium dioxide results in increased expression of CCL2 protein | PMID:19464567 PMID:21259345 PMID:23557971 PMID:27760801 | Ccl2 | increases expression | ISO | CCL2 (Homo sapiens) | 6480464 | CTD | titanium dioxide results in increased expression of CCL2 mRNA | PMID:19695317 PMID:22342292 | Ccl2 | increases secretion | ISO | CCL2 (Homo sapiens) | 6480464 | CTD | titanium dioxide results in increased secretion of CCL2 protein | PMID:25526690 | Ccl2 | multiple interactions | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CCL2 mRNA; titanium dioxide promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL2 protein] | PMID:27216632 PMID:29950665 | Ccl2 | multiple interactions | ISO | CCL2 (Homo sapiens) | 6480464 | CTD | [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of CCL2 protein | PMID:30711708 | |
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