GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Kcnq1 | decreases activity | ISO | KCNQ1 (Homo sapiens) | 6480464 | CTD | Bupivacaine results in decreased activity of KCNQ1 protein | PMID:16931984 | Kcnq1 | increases response to substance | ISO | KCNQ1 (Homo sapiens) | 6480464 | CTD | KCNQ1 protein mutant form results in increased susceptibility to Bupivacaine | PMID:16931984 | Kcnq1 | multiple interactions | ISO | KCNQ1 (Homo sapiens) | 6480464 | CTD | Bupivacaine results in decreased activity of [KCNQ1 protein binds to KCNE1 protein]; KCNE1 protein inhibits the reaction [KCNQ1 protein mutant form results in increased susceptibility to Bupivacaine] | PMID:16931984 | |
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