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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1617574 Species: Mus musculus RGD Object: Gene Symbol: Ear5 Name: eosinophil-associated, ribonuclease A family, member 5

Acc ID: CHEBI:3207 Term: budesonide Definition: A glucocorticoid steroid having a highly oxygenated pregna-1,4-diene structure. It is used mainly in the treatment of asthma and non-infectious rhinitis and for treatment and prevention of nasal polyposis. CasRN: 51333-22-3 Chemical ID: MESH:D019819

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:1352667	6480464	CTD	Budesonide results in decreased expression of RNASE3 protein	PMID:15612964