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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620349
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: CHEBI:31860
Term: Mofezolac (TN)
Definition: null
Chemical ID: MESH:C054999
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgs2decreases activityEXP 6480464CTDmofezolac results in decreased activity of PTGS2 proteinPMID:9450688
Ptgs2multiple interactionsEXP 6480464CTDmofezolac inhibits the reaction [[PTGS2 protein results in increased chemical synthesis of Prostaglandins] which results in increased expression of FOS mRNA]PMID:9450688
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