GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rela | affects localization | EXP | | 6480464 | CTD | lead acetate affects the localization of RELA protein | PMID:22728154 PMID:25088297 | Rela | increases expression | EXP | | 6480464 | CTD | lead acetate results in increased expression of RELA mRNA; lead acetate results in increased expression of RELA protein | PMID:37866543 | Rela | multiple interactions | EXP | | 6480464 | CTD | Ascorbic Acid inhibits the reaction [lead acetate affects the localization of RELA protein]; Proanthocyanidins inhibits the reaction [lead acetate affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in increased expression of RELA protein]; Quercetin inhibits the reaction [lead acetate affects the localization of RELA protein] | PMID:22728154 PMID:25088297 PMID:37866543 | Rela | affects localization | ISO | Rela (Mus musculus) | 6480464 | CTD | lead acetate affects the localization of RELA protein | PMID:24530660 | Rela | decreases expression | ISO | Rela (Mus musculus) | 6480464 | CTD | lead acetate results in decreased expression of RELA mRNA | PMID:24260418 | Rela | increases expression | ISO | Rela (Mus musculus) | 6480464 | CTD | lead acetate results in increased expression of RELA mRNA; lead acetate results in increased expression of RELA protein | PMID:24260418 PMID:36539177 PMID:37385299 | Rela | multiple interactions | ISO | Rela (Mus musculus) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [lead acetate results in increased expression of RELA protein]; 3,4-di-O-caffeoylquinic acid inhibits the reaction [lead acetate results in increased expression of RELA protein]; [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with U 0126] inhibits the reaction [lead acetate results in increased expression of RELA protein]; lead acetate results in increased phosphorylation of and results in increased expression of RELA protein; pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in increased expression of RELA protein]; U 0126 inhibits the reaction [lead acetate results in increased expression of RELA protein] | PMID:24530660 PMID:36539177 PMID:37385299 | |
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