Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620817
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aifm1
Name: apoptosis inducing factor, mitochondria associated 1
Acc ID: CHEBI:31767
Term: lead diacetate
Definition: A lead coordination entity in which a central lead(2+) atom is coordinated to two acetate ions.
Chemical ID: MESH:C008261
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aifm1affects expressionEXP 6480464CTDlead acetate affects the expression of AIFM1 proteinPMID:18618274
Aifm1decreases expressionEXP 6480464CTDlead acetate results in decreased expression of AIFM1 mRNAPMID:23146751
Aifm1multiple interactionsISOAIFM1 (Homo sapiens)6480464CTD[amyloid beta-protein (1-40) co-treated with amyloid beta-protein (25-35)] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of AIFM1 protein]; [lead acetate results in increased abundance of Lead] which results in increased expression of AIFM1 protein; amyloid beta-protein (1-40) promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of AIFM1 protein]; amyloid beta-protein (25-35) promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of AIFM1 protein]; PPIF protein affects the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of AIFM1 protein]PMID:31874198 PMID:35300571
Go Back to source page   Continue to Ontology report