GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gria1 | decreases expression | EXP | | 6480464 | CTD | Kainic Acid results in decreased expression of GRIA1 mRNA; Kainic Acid results in decreased expression of GRIA1 protein | PMID:17585341 PMID:7529610 | Gria1 | multiple interactions | EXP | | 6480464 | CTD | 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Kainic Acid results in decreased expression of GRIA1 protein]; Kainic Acid binds to and results in increased activity of GRIA1 protein; Urethane inhibits the reaction [Kainic Acid binds to and results in increased activity of GRIA1 protein] | PMID:11812690 PMID:17585341 | Gria1 | decreases expression | ISO | Gria1 (Mus musculus) | 6480464 | CTD | Kainic Acid results in decreased expression of GRIA1 mRNA | PMID:21589914 | Gria1 | increases phosphorylation | ISO | Gria1 (Mus musculus) | 6480464 | CTD | Kainic Acid results in increased phosphorylation of GRIA1 protein | PMID:34352349 | Gria1 | multiple interactions | ISO | Gria1 (Mus musculus) | 6480464 | CTD | Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIA1 mRNA]; Kainic Acid inhibits the reaction [cyanoginosin LR results in increased expression of and results in increased phosphorylation of GRIA1 protein]; PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIA1 mRNA] | PMID:21589914 PMID:34352349 | | ||||||||||||||||||||||
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