GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp1a1 | increases expression | ISO | CYP1A1 (Homo sapiens) | 6480464 | CTD | Fulvestrant results in increased expression of CYP1A1 mRNA | PMID:19901195 PMID:28985473 PMID:31646340 | Cyp1a1 | multiple interactions | ISO | Cyp1a1 (Mus musculus) | 6480464 | CTD | fulvestrant inhibits the reaction [Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]] | PMID:12093619 | Cyp1a1 | multiple interactions | ISO | CYP1A1 (Homo sapiens) | 6480464 | CTD | [Fulvestrant results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; Fulvestrant inhibits the reaction [daidzein results in decreased expression of CYP1A1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of CYP1A1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of CYP1A1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of CYP1A1 protein]; Fulvestrant inhibits the reaction [Genistein results in decreased expression of CYP1A1 mRNA]; Fulvestrant inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1A1 promoter]]; Fulvestrant promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Fulvestrant promotes the reaction [biochanin A results in increased expression of CYP1A1 mRNA]; Fulvestrant promotes the reaction [formononetin results in increased expression of CYP1A1 mRNA]; Fulvestrant promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] | PMID:10619402 PMID:19460354 PMID:19901195 PMID:21513769 PMID:28618207 PMID:28985473 PMID:31646340 | |
Go Back to source page | Continue to Ontology report |