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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619951
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb1a
Name: ATP binding cassette subfamily B member 1A
Acc ID: CHEBI:31516
Term: Doramectin
Definition: null
Chemical ID: MESH:C084101
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb1adecreases activityISOAbcb1a (Mus musculus)6480464CTDdoramectin results in decreased activity of ABCB1A proteinPMID:17134887
Abcb1adecreases expressionISOAbcb1a (Mus musculus)6480464CTDdoramectin results in decreased expression of ABCB1A proteinPMID:19879343
Abcb1adecreases expressionISOABCB1 (Homo sapiens)6480464CTDdoramectin results in decreased expression of ABCB1 mRNA; doramectin results in decreased expression of ABCB1 proteinPMID:20487225
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