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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71014
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adcy5
Name: adenylate cyclase 5
Acc ID: CHEBI:31429
Term: colforsin daropate hydrochloride
Definition: The hydrochloride salt of colforsin daropate. It is a drug used for the treatment of acute heart failure. It directly stimulates adenylate cyclase and produces positive inotropic and vasodilator effects accompanied by the increase in cellular cAMP.
Chemical ID: MESH:D005576
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adcy5multiple interactionsISOAdcy5 (Mus musculus)6480464CTDADCY5 protein results in increased susceptibility to [Colforsin co-treated with Quinpirole]PMID:12223546
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