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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620651
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cd55
Name: CD55 molecule (Cromer blood group)
Acc ID: CHEBI:31429
Term: colforsin daropate hydrochloride
Definition: The hydrochloride salt of colforsin daropate. It is a drug used for the treatment of acute heart failure. It directly stimulates adenylate cyclase and produces positive inotropic and vasodilator effects accompanied by the increase in cellular cAMP.
Chemical ID: MESH:D005576
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cd55increases expressionISOCD55 (Homo sapiens)6480464CTDColforsin results in increased expression of CD55 mRNAPMID:22553215
Cd55multiple interactionsISOCD55 (Homo sapiens)6480464CTD3',4'-dimethoxy-alpha-naphthoflavone inhibits the reaction [Colforsin results in increased expression of CD55 mRNA]PMID:22553215
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