GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tp53 | increases expression | ISO | Trp53 (Mus musculus) | 6480464 | CTD | Bleomycin results in increased expression of TRP53 protein | PMID:9683175 | Tp53 | increases expression | ISO | TP53 (Homo sapiens) | 6480464 | CTD | Bleomycin results in increased expression of TP53 mRNA | PMID:26800624 | Tp53 | increases phosphorylation | ISO | TP53 (Homo sapiens) | 6480464 | CTD | Bleomycin results in increased phosphorylation of TP53 protein | PMID:24933654 | Tp53 | increases response to substance | ISO | TP53 (Homo sapiens) | 6480464 | CTD | TP53 protein results in increased susceptibility to Bleomycin | PMID:20135637 | Tp53 | multiple interactions | ISO | TP53 (Homo sapiens) | 6480464 | CTD | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [Resveratrol results in increased phosphorylation of TP53 protein]]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin results in increased phosphorylation of TP53 protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]]; Bleomycin promotes the reaction [Polyphenols results in increased expression of TP53 mRNA]; Bleomycin promotes the reaction [Resveratrol results in increased phosphorylation of TP53 protein]; Bleomycin promotes the reaction [Tea results in increased expression of TP53 mRNA]; Polyphenols promotes the reaction [Bleomycin results in increased expression of TP53 mRNA]; Resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]; Tea promotes the reaction [Bleomycin results in increased expression of TP53 mRNA] | PMID:24933654 PMID:26800624 | | ||||||||||||||||||||||
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