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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620640
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2d4
Name: cytochrome P450, family 2, subfamily d, polypeptide 4
Acc ID: CHEBI:30958
Term: Sudan I
Definition: An azo compound that has formula C16H12N2O.
Chemical ID: MESH:C024336
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2d4increases oxidationISOCYP2D6 (Homo sapiens)6480464CTDCYP2D6 protein results in increased oxidation of 1-phenylazo-2-naphtholPMID:17159775
Cyp2d4multiple interactionsISOCYP2D6 (Homo sapiens)6480464CTDCYB5A protein inhibits the reaction [CYP2D6 protein results in increased oxidation of 1-phenylazo-2-naphthol]PMID:17159775
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