GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp1a2 | increases expression | EXP | | 6480464 | CTD | 1-phenylazo-2-naphthol results in increased expression of CYP1A2 mRNA | PMID:26845733 | Cyp1a2 | multiple interactions | EXP | | 6480464 | CTD | 1-phenylazo-2-naphthol affects the expression of and affects the activity of CYP1A2 protein; [1-phenylazo-2-naphthol co-treated with aristolochic acid I] results in increased expression of CYP1A2 mRNA; [aristolochic acid I co-treated with 1-phenylazo-2-naphthol] results in increased expression of and results in increased activity of CYP1A2 protein | PMID:26845733 | Cyp1a2 | increases oxidation | ISO | CYP1A2 (Homo sapiens) | 6480464 | CTD | CYP1A2 protein results in increased oxidation of 1-phenylazo-2-naphthol | PMID:17159775 | Cyp1a2 | multiple interactions | ISO | CYP1A2 (Homo sapiens) | 6480464 | CTD | CYB5A protein promotes the reaction [CYP1A2 protein results in increased oxidation of 1-phenylazo-2-naphthol] | PMID:17159775 | |
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