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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3317
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pgr
Name: progesterone receptor
Acc ID: CHEBI:3093
Term: bifenthrin
Definition: A carboxylic ester obtained by formal condensation of cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylic acid and [(2-methyl-1,1'-biphenyl)-3-yl]methanol.
Chemical ID: MESH:C099952
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pgrmultiple interactionsEXP 6480464CTDbifenthrin inhibits the reaction [CGA protein results in increased expression of PGR mRNA]PMID:21251947
Pgrincreases expressionISOPGR (Homo sapiens)6480464CTDbifenthrin results in increased expression of PGR; bifenthrin results in increased expression of PGR mRNAPMID:24938463
Pgrmultiple interactionsISOPGR (Homo sapiens)6480464CTDfulvestrant inhibits the reaction [bifenthrin results in increased expression of PGR mRNA]PMID:24938463
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