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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2459
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1a2
Name: cytochrome P450, family 1, subfamily a, polypeptide 2
Acc ID: CHEBI:30786
Term: dimethylmercury
Definition: A methylmercury compound that has formula C2H6Hg.
Chemical ID: MESH:C073972
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a2decreases expressionEXP 6480464CTDdimethyl mercury results in decreased expression of CYP1A2 proteinPMID:21424224
Cyp1a2multiple interactionsEXP 6480464CTD[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP1A2 protein]PMID:21424224
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