Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2543
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Egfr
Name: epidermal growth factor receptor
Acc ID: CHEBI:30778
Term: gallic acid
Definition: A trihydroxybenzoic acid in which the hydroxy groups are at positions 3, 4, and 5.
Chemical ID: MESH:D005707
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Egfrmultiple interactionsISOEGFR (Homo sapiens)6480464CTD[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; Gallic Acid inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; SRC protein modified form affects the reaction [Gallic Acid inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]]; SRC protein modified form inhibits the reaction [Gallic Acid inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]]PMID:27087131 PMID:27634460
Go Back to source page   Continue to Ontology report