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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71101
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc3
Name: ATP binding cassette subfamily C member 3
Acc ID: CHEBI:30621
Term: diarsenic trioxide
Definition: An arsenic oxide in which arsenic and oxygen atoms are present in the ratio 2:3.
Chemical ID: MESH:C006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc3decreases expressionISOABCC3 (Homo sapiens)6480464CTDArsenic Trioxide results in decreased expression of ABCC3 mRNAPMID:22214486
Abcc3decreases response to substanceISOABCC3 (Homo sapiens)6480464CTDABCC3 protein results in decreased susceptibility to Arsenic TrioxidePMID:20707922
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