GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Itgam | decreases expression | ISO | ITGAM (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in decreased expression of ITGAM protein | PMID:16174796 | Itgam | decreases expression | ISO | Itgam (Mus musculus) | 6480464 | CTD | Arsenic Trioxide results in decreased expression of ITGAM protein | PMID:27461142 | Itgam | increases expression | ISO | ITGAM (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in increased expression of ITGAM mRNA; Arsenic Trioxide results in increased expression of ITGAM protein | PMID:10648417 PMID:16430862 PMID:16468075 PMID:20226526 PMID:25758096 PMID:32587277 | Itgam | increases expression | ISO | Itgam (Mus musculus) | 6480464 | CTD | Arsenic Trioxide results in increased expression of ITGAM protein | PMID:20609355 | Itgam | multiple interactions | ISO | ITGAM (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Sirolimus co-treated with Arsenic Trioxide] results in increased expression of ITGAM protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased expression of ITGAM protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Gefitinib promotes the reaction [Arsenic Trioxide results in increased expression of ITGAM protein]]; [Arsenic Trioxide co-treated with Tretinoin] results in increased expression of ITGAM protein; [Sirolimus co-treated with Arsenic Trioxide] results in increased expression of ITGAM protein; [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of ITGAM mRNA; AG 1879 promotes the reaction [[Arsenic Trioxide co-treated with Tretinoin] results in increased expression of ITGAM protein]; Arsenic Trioxide promotes the reaction [Tretinoin results in increased expression of ITGAM protein]; Gefitinib promotes the reaction [Arsenic Trioxide results in increased expression of ITGAM mRNA]; Gefitinib promotes the reaction [Arsenic Trioxide results in increased expression of ITGAM protein] | PMID:16468075 PMID:20226526 PMID:20615082 PMID:24953245 PMID:25758096 | Itgam | multiple interactions | ISO | Itgam (Mus musculus) | 6480464 | CTD | ATF4 protein affects the reaction [Arsenic Trioxide results in decreased expression of ITGAM protein] | PMID:27461142 | | ||||||||||||||||||||||
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