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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2047
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adm
Name: adrenomedullin
Acc ID: CHEBI:30621
Term: diarsenic trioxide
Definition: An arsenic oxide in which arsenic and oxygen atoms are present in the ratio 2:3.
Chemical ID: MESH:C006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Admdecreases expressionISOADM (Homo sapiens)6480464CTDArsenic Trioxide results in decreased expression of ADM mRNAPMID:20471514
Admincreases expressionISOADM (Homo sapiens)6480464CTDArsenic Trioxide results in increased expression of ADM mRNAPMID:19128835
Admmultiple interactionsISOADM (Homo sapiens)6480464CTDBortezomib inhibits the reaction [Arsenic Trioxide results in decreased expression of ADM mRNA]PMID:20471514
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