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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2953 Species: Rattus norvegicus RGD Object: Gene Symbol: Kcna5 Name: potassium voltage-gated channel, shaker-related subfamily, member 5

Acc ID: CHEBI:3061 Term: bepridil Definition: A tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl. CasRN: 64706-54-3 Chemical ID: MESH:D015764

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases activity	ISO	RGD:731065	6480464	CTD	Bepridil results in decreased activity of KCNA5 protein	PMID:11711026